|ECR 2019 / C-2469|
|Early choroid plexus invasion as a risk factor of non-effective postoperative glioblastoma radiotherapy|
Among 63 patients 42 (66.7%) showed progressive disease and 21 (33.3%) were stable or showed partial response in 6-months period after competing chemoradiation. Data optained within 1 month and 3 months after postoperative treatment showed similar results.
Patients with invaded CP showed progression after therapy in 80.8% cases while patients without invasion of CP - in 56.6%. The sensitivity and specificity of method were 0.50 and 0.76, but the positive predictive value showed 80.8% (p=0.033).
Due to high arterial input and venous drainage of invaded choroid vessels the standard postoperative therapy of partial resected glioblastomas seems ineffective in 80.8% of observed patients.
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