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ECR 2019 / C-1042
The enhancement pattern of arterial phase on MRI potentially predicts pancreatic neuroendocrine tumours with somatostatin receptor-2 expression
Congress: ECR 2019
Poster No.: C-1042
Type: Scientific Exhibit
Keywords: Abdomen, Oncology, Pancreas, MR, MR-Diffusion/Perfusion, MR-Functional imaging, Contrast agent-intravenous, Outcomes analysis, Surgery, Cancer, Pathology
Authors: Y. Hu; Shanghai/CN
DOI:10.26044/ecr2019/C-1042

Results

 13 tumors with negative SSTR2 and 52 tumors with positive SSTR2 were evaluated. The positive SSTR2 group showed male(48.1% vs 84.6%,P < 0.05 ), hypointense signal on arterial phase (23.1% vs 76.9%, P < 0.05), portal venous phase (13.5% vs 61.5%, P < 0.05), and delayed phase (9.6% vs46.2%, P < 0.05) less frequently than the negative SSTR2 group, as opposed to the G1(34.6 % vs 7.7%,P < 0.05 ). However, The CNRs of arterial phase of the positive SSTR2 group were larger than the negative SSTR2 group (-0.0097 vs -0.7953, P<0.05). Using binary logistic regression analysis, the contrast enhancement on arterial phase was an independent significant differentiator of the positive SSTR2 group from the negative SSTR2 group. The optimal cut-off value for the identification of the positive SSTR2 group was hyper/isointense signal on arterial phase (sensitivity 75.47%, specificity 76.92%).

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