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ECR 2019 / C-0525
Influence of ROI placement: different ADC metrics on diagnostic accuracy of DWI in NME breast tumours
Congress: ECR 2019
Poster No.: C-0525
Type: Scientific Exhibit
Keywords: Breast, Oncology, Anatomy, MR, MR-Diffusion/Perfusion, MR-Functional imaging, Imaging sequences, Contrast agent-intravenous, Biopsy, Cancer, Neoplasia
Authors: D. B. Avendano1, M. A. Marino2, D. Leithner3, B. Bernard-Davila4, T. H. Helbich5, E. A. Morris6, M. S. Jochelson6, P. A. T. Baltzer5, K. Pinker-Domenig5; 1Monterrey, Nuevo leon/MX, 2Messina/IT, 3Frankfurt/DE, 4New York/US, 5Vienna/AT, 6New York, NY/US


66 patients (mean ages 51.8 ±10.8 yo, range 26-76 yo) were included for analysis with a mean size lesion of 40±25 mm, range 5 mm-98 mm): 39 (59%) malignant and 27 (42%) benign (see Fig. 3). 

29 patients excluded; 5 insufficient quality DWI images (24 NME lesions not discernable on DWI alone (12 benign/12 malignant).

The best diagnostic performance for DWI for both readers and readings were achieved with Dptu mean with AUC range 0.512 and 0.709 (Fig 4). 

CCC varied among the different ADC metrics was fair-to-moderate. 

the best results for CCC were achived for Dptu max ADC (0.420) in second reading (fig 5). 

Similar results were obtained for intra-reader agreement with the best CCC for Wtu mean, R1 0.435 and R20.412 (fig. 6)  


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