|ECR 2019 / C-2408|
|Utility of percutaneous image-guided biopsies of retroperitoneal masses prior to surgical resection|
Methods and materials
Patient population: Patients that underwent biopsy and/or surgical resection of retroperitoneal masses at a single institution from 01/2009 to 12/2017 were included in this study. All patients underwent a pre-surgical MRI or CT study. Pre-procedural chemotherapy or radiotherapy was not performed.
Data acquisition: Patient age and sex, preoperative history and physical examination, radiology diagnosis, surgeon diagnosis, and pathology data were collected. The histological diagnosis of the resected mass was compared to the radiologic and surgical differential diagnosis prior to resection.
Evaluation: All cases were anonymized and the preoperative information (preoperative imaging and preoperative history and physical examination) were reviewed by an independent expert surgeon. We simulated the management of these cases assuming the diagnosis was known and compared clinical management in cases without preoperative biopsies to that expected if preoperative biopsies were performed. The proportion of cases where clinical management would have changed, the time to delay in appropriate treatment, and length of hospital stay were recorded. Change in clinical management was defined as whether optimal therapy included neoadjuvant preoperative radiotherapy, neoadjuvant preoperative chemotherapy, a different surgical approach or procedure, or no surgery. Additionally, patient symptomatology and clinical status was included in the consideration of optimal therapy.
Statistical analysis: Proportions were compared using Fisher’s exact tests.
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