|ECR 2019 / C-1792|
|Is MRI diffusion-weighted imaging a reliable tool for the diagnosis and post therapeutic follow up of extremity soft‑tissue neoplasms?|
Regarding inital evaluation of soft tissue masses
A significant overlap between benign & malignant masses as benign & malignant ADC values were (mean ADC=1.2 x 10-3 mm2/sec & 1.31 x 10-3 mm2/sec ,respectively).
Mean ADC values for benign non myxoid tumors, myxoid malignant tumors & non myxoid malignant tumors were 1.2× 10-3 mm2/sec, 2.6× 10-3 mm2/sec & 1.1× 10-3 mm2/sec.
Newly diagnosed fibromatosis patients mean ADC values were 1.31 ± 0.25 × 10-3 mm2/sec)
Regarding post-therapeutic follow up
Follow up soft tissue sacromas patients showed that lesions of a favourable theeapeutic response had increase of recorded ADC values about 0.28 x10-3 mm 2 /s between pre & post-therapy corresponding well to the decreased overall tumoral volume & enhancement pattern.
Follow up fibromatosis patients in our study showed that lesions of a favorable response to chemo- or radiotherapy exhibited lower ADC values than those showing a progressive disease course.
In conclusion, diffusion-weighted imaging with ADC mapping of extremity soft tissue tumors is so complicated that they alone may not be useful in differentiating between benign and malignant tumors. DWI with ADC mapping can be used as a tool for monitoring response to treatment.
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