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ECR 2019 / C-0763
Pancreatic and Biliary Involvement in IgG4-Related Disease: What the Radiologist Needs to Know
Congress: ECR 2019
Poster No.: C-0763
Type: Educational Exhibit
Keywords: Education and training, Diagnostic procedure, MR-Cholangiography, MR, CT, Pancreas, Biliary Tract / Gallbladder, Abdomen
Authors: J. Miguez Gonzalez, P. LOZANO ARRANZ, R. Oliveira Caiafa, F. Calaf Forn, A. Thomas, J. Catala Forteza; Barcelona/ES
DOI:10.26044/ecr2019/C-0763

Conclusion

Autoimmune Pancreatitis and IgG4-Related Sclerosing Cholangitis are the two main ways of pancreatic and biliary involvement in IgG4-Related Disease. They have distinctive radiological features on CT and MRI (Fig. 22) that must be known by the radiologist in order to allow an early diagnosis and an optimal therapeutic approach, avoiding misdiagnosis with other diseases and unnecesary invasive procedures. Both entities are associated in up to 80-90% of cases and share clinical symptoms, presenting usually as a painless or mildly symptomatic obstructive jaundice in a 40 to 70 year-old man with elevation of serum levels of IgG4 and dramatic response to steroids (Fig. 23). The presence of IgG4-related disease in other organs is not uncommon and supports the diagnosis. 

 

Fig. 22
References: Radiology, Hospital Sant Joan Despi Moises Broggi - Barcelona/ES

 

Fig. 23
References: Radiology, Hospital Sant Joan Despi Moises Broggi - Barcelona/ES

 

 

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