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ECR 2019 / C-3447
Rare localizations of malignant Solitary Fibrous Tumors (SFT): clinical presentation and radiological characteristics
Congress: ECR 2019
Poster No.: C-3447
Type: Educational Exhibit
Keywords: Neoplasia, Multidisciplinary cancer care, Diagnostic procedure, MR, CT, Oncology, Musculoskeletal soft tissue
Authors: N. Gennaro, A. Marrari, O. G. Santonocito, S. Imparato, L. Balzarini; Rozzano/IT
DOI:10.26044/ecr2019/C-3447

Findings and procedure details

We searched though our Institutional databse all biopsy-proven diagnosis of SFTs with atypical presentations (extrapleural and extraperitoneal tumors). 

In particular, we describe 3 cases of atypical localizations of SFTs with their CT, MR, US and PET characteristics. 

 

 

CASE 1 

 

Initially misdiagnosed as lymphadenopathy, this submandibular mass was later confirmed to be a SFT (CD34+, Bcl2+, CD99+).

Color Doppler US shows a vascularized hypoechoic mass in the submandibular region. US-guided core needle biopsy was subsequently performed to confirm the diagnosis.  

MRI showed hyperintense mass in CE axial/coronal/sagittal T1W, mildly hipointense in both axial T2W STIR and T2 and highy hyperintense in DWI b=800.

 

 

CASE 2 

 

Diffuse aspecific arthralgia was caused by a SFT localized in the left thigh. Pathology confirmed the diagnosis of SFT (CD34+, S100-, EMA-, Somatostatin receptor II, III, V A/B).

68Ga-DOTA-TOC PET/CT shows an avid soft tissue lesion in the left thigh.

MRI showed mildly hyperintensity in coronal FS-T2W, as well as in CE coronal and axial T1W.

 

CASE 3 

 

Nasal obstruction and bleeding were caused by nasal localization of SFT.

Pathology confirmed the diagnosis of SFT (MIB1 10%, CD34 +, CD31 +, ActinML+, Factor XIII+, Patient 1).

CT showed a hypodense lesion within the left nasal cavity at coronal/sagittal unenhanced CT.

MRI showed a strongly hyperintense lesion in CE coronal T1W, as well as in the unenhanced sagittal T1W sequence.

In sagittal T2W the lesion appeared slightly hyperintense.

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