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ESCR 2017 / P-0095
Stress Evaluation using Functional MRI in patients with Coronary Artery Disease
Congress: ESCR 2017
Poster No.: P-0095
Type: Scientific Poster
Keywords: Image registration, Arteriosclerosis, Experimental investigations, Diagnostic procedure, MR-Functional imaging, Neuroradiology brain, Cardiovascular system, Cardiac
Authors: M. Zashezova, D. Ustyuzhanin, M. Shariya, R. Konovalov, N. Serova, S. K. Ternovoy; Moscow/RU

Results

In simulated stressful situations CAD patients differed from healthy individuals having increased values of galvanic skin response (GSR) and decreased power of the alpha rhythm in background electroencephalogram (EEG). Psychological indicators of chronic stress (PSM-25 questionnaire) were significantly higher in the experimental group. 

 

Functional MRI study analysis showed a decrease in the total volume of the activation zones in response to stress in patients with CAD (Fig.1,2).

 

 

Fig. 1: Brain activation map in response to stress in healthy volunteers group.
References: Dept. of Tomography, Cardiology Research Center - Moscow/RU

Brain activation map in response to stress in healthy volunteers group you can see on fig. 1.

 

 

Fig. 2: Brain activation map in response to stress in patients with CAD.
References: Dept. of Tomography, Cardiology Research Center - Moscow/RU

Fig. 2 showed brain activation map in response to stress in patients with CAD.

 

In addition, activation zones in patients with CAD were found in the right insula (Fig.3) and the left cingulate cortex (Fig.4).

 

 

Fig. 3: Activation zone in the right insula in response to stress in patients with CAD.
References: Dept. of Tomography, Cardiology Research Center - Moscow/RU

Activation zone in the right insula in response to stress in patients with CAD you can find on fig. 3.

 

 

Fig. 4: Activation zone in the left cingulate cortex in response to stress in patients with CAD.
References: Dept. of Tomography, Cardiology Research Center - Moscow/RU

Fig. 4 showed activation zone in the left cingulate cortex in response to stress in patients with CAD.

 

The revealed neuronal activation in response to stress influence proves the participation of the insula and the cingulate cortex in regulation of stressful behavior.

 

 

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