|ESCR 2017 / P-0089|
|Three dimensional modelling in structural heart disease: How can LGE MRI help electrophysiologist?|
Methods and Materials
Study enrolled 25 patients (pts) with prior myocardial infarction(MI).
- 24-hour ECG monitoring;
- body surface electroanatomical activation mapping with reconstruction of LV 3D models for location the VA origin. On 3D models of LV electroanatomic isopotentioal and isochrone maps were reconstructed. On theese maps the location of VA origin was detected as a point of earliest electrical activation.
- LGE MRI on 1.5 T clinical scanner using high resolution(1.25x1.25x2.5mm) inversion-recovery pulse sequence (TI 290-340ms, TE 2,4ms, TR 750-950ms). On obtained images LV myocardium epicardial end endocardial surface were segmented manually. Scar tissue threshold was 3.5SD above the mean LV signal intensity(SI), GZ threshold was 2.5-3.5SD above the mean LV SI. Scar and GZ were mapped on reconstructed 3D models of LV structure.
- Both 3D models of LV structure and LV electroanatomical maps were divided into 17 segments manually. Both these 3D models were evaluated simultaneously by two experts (radiologist and electriphysiologist). The ralations between location of VA in comparison with the LV myocardial structure were assessed.
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