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ECR 2015 / C-0664
Value of bimodal 18F-Choline-PET/MRI and trimodal 18F-Choline-PET/MRI/TRUS for the assessment of prostate cancer recurrence after radiation therapy and radical prostatectomy
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Congress: ECR 2015
Poster No.: C-0664
Type: Educational Exhibit
Keywords: Prostheses, Technical aspects, Diagnostic procedure, Computer Applications-Virtual imaging, Ultrasound, PET-CT, MR, Pelvis, Oncology, Genital / Reproductive system male
Authors: L. Cevasco, F. Paparo, L. Bacigalupo, R. Piccazzo, C. Puppo, E. Aleo, G. A. Rollandi; Genoa/IT


The performance of pelvic mpMRI is superior to that of choline-PET in depicting local relapse after RP and RT, whereas choline PET/CT is more accurate than mpMRI in detecting metastatic disease in pelvic lymph nodes. Both modalities are excellent in the assessment of skeletal metastases. The combination of mpMRI and choline-PET/CT provides a comprehensive assessment for the restaging of patients with biochemical recurrence after RP and RT, thus allowing local recurrence to be distinguished from metastatic disease. Bimodal 18F-choline-PET/mpMRI fusion imaging provides simultaneous reading and interpretation of the two different modalities; this enables morphological, functional and metabolic information to be combined, hence overcoming the limitations of each separate imaging modality. In addition, trimodal 18F-choline-PET/mpMRI/TRUS fusion imaging may be useful for planning and guiding biopsy procedures in order to obtain histological confirmation of the local recurrence.

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