ECR 2014 / C-2302
Correlation between Perfusion Micro-Bubble Ultrasound and Perfusion Contrast Enhanced MRI for Carotid Plaque Neovascularization
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Congress: ECR 2014
Poster No.: C-2302
Type: Scientific Exhibit
Keywords: Tissue characterisation, Image registration, Segmentation, Contrast agent-intravenous, Ultrasound, MR, Vascular, Neuroradiology brain, Contrast agents
Authors: W. Abutaleb1, M. J. Graves2, J. H. Gillard2; 1Riyadh/SA; Cambridge/UK, 2Cambridge/UK




  The present study provides preliminary evidence to suggest that intraplaque neovascularisation detected by DCE-US is associated with its presence in established method using DCE-MRI Kinetic Modelling. However, this correlation is not quite significant. 


    If larger sample proove more significance, that will introduce higher flexibility for potential clinical application of the two modalities. 


      So as an answer to my earlier quistion: if all the roads leads to Rome: it seems very likely however; we should expect differences in the approach and may be in the effort we have to put to discover the shortest and safest road.





  1. Sample size is small to give significant results, we are acquiring more data which should increase the statistical significant of the results. 


  2. Even we are scanning the same patients, and the same diseased part of the carotid, it is unattainable to scan the exact plane in both DCE-MR, as a cross sectional imaging modality, and the DCE-US. The 3d transducer was one of the proposed solutions. However, the available frequency of that type of transducer is not in the suitable range for carotid DCE-US imaging. That could explain missed correlation in some cases as the data could have been assembled from slightly different sections of the plaque.

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