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ECR 2014 / C-0306
Repeated CT examinations, radiation dose and attributable cancer risk in patients with lymphoma
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Congress: ECR 2014
Poster No.: C-0306
Type: Scientific Exhibit
Keywords: Lymphoma, Dosimetric comparison, Biological effects, Radiation safety, Radiation effects, Dosimetry, MR-Diffusion/Perfusion, CT, Radioprotection / Radiation dose, Oncology, Lymph nodes
Authors: S. Kharuzhyk, E. Leusik; Minsk/BY
DOI:10.1594/ecr2014/C-0306

Conclusion

In patients with lymphoma treated in our institution in 2010-2011 it were performed 13.3 CT exams in average (interval 3-29 exams) per patient during entire period of diagnosis, treatment and follow-up. Biggest proportion of CTs was performed during chemotherapy followed by exams after the end of treatment. Thoracic CT was the most often examination. Mean cumulative effective dose was 86.7 mSv (interval 21.7-209.2 mSv) per patient. Attributable risk of cancer was 0.176 for the whole group equaling 1 additional cancer case per 256 patients. Our findings on attributable to CT risk of developing cancer correspond to the data of other authors [6-8]. However, the attributable risk of cancer is a quite low compared to the baseline risk of getting cancer. In addition, the value of attributable risk cannot be applied at the level of the individual patient.

 

In conclusion, repeated CT exams in patients with lymphoma result in a relatively high cumulative effective dose which may exceed 200 mSv. In this regard, it is advisable to consider the use of other non-irradiating radiological modalities such as MRI with diffusion-weighted imaging. Another important way of reducing patient dose is to optimize CT scanning protocols.

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