Brought to you by
ECR 2013 / C-2669
Rapid bedside assessment of the renal function of patients undergoing contrast-enhanced CT. Is it a reliable approach for identifying patients at risk of a contrast medium adverse reaction ?. 
Congress: ECR 2013
Poster No.: C-2669
Type: Scientific Exhibit
Keywords: CT, Kidney, Contrast agents, Laboratory tests, Drugs / Reactions
Authors: A. Wibmer1, R. Nolz1, G. Heinz-Peer2; 1Wien/AT, 2St. Pölten/AT
DOI:10.1594/ecr2013/C-2669

Results

The laboratory gold standard yielded a significantly higher mean eGFR value  when compared to the capillary and venous blood analysis of the StatSensor® (p<0.001, respectively). Agreement plots and Bland-Altman plots are for the venous measurements are shown in Figures 1 and 2, those for the capillary measurement are shown in Figure 3 and 4. These plots show a good agreement of eGFR-values calculated on the basis of the StatSensor® creatinine measurements and the gold standard. This was especially true for patients with an eGFR<90 ml/min/1.73m². Diagnostic accuracy of the StatSensor® was evaluated by its potential to discriminate patients with normal from those with abnormal renal function, with an eGFR of 30, 45 and 60 ml/min/1.73m² as cut-off, respectively. Table 2 gives information about sensitivity, specificity, positive and negative predictive values and accuracy when compared to the gold-standard.

 

 

Sample

Cut-off eGFR (ml/min/1.73m²)

Sensitivity

Specificity

ppV

npV

Accuracy

Capillary Blood

60

0.87

0.87

0.62

0.96

0.87

45

1.00

0.95

0.60

1.00

0.96

30

1.00

0.99

0.40

1.00

0.99

Venous Blood

60

0.85

0.90

0.67

0.96

0.89

45

1.00

0.96

0.63

1.00

0.96

30

1.00

0.99

0.43

1.00

0.99

 

 It shows a 100% sensitivity for the detection of patients with an eGFR <30 and <45 ml/min/1.73m², while sensitivity was lower if a cut-off eGFR of 60 ml/min/1.73m² was chosen. Negative predictive value was >96% for all three cut-off eGFR values, for capillary as well as venous blood analysis. Specificity ranged from 87% to 99%, depending on the eGFR cut-off value. Positive predictive values varied between 40% and 67%. 

POSTER ACTIONS Add bookmark Contact presenter Send to a friend Download pdf
SHARE THIS POSTER
2 clicks for more privacy: On the first click the button will be activated and you can then share the poster with a second click.

This website uses cookies. Learn more