|ECR 2011 / C-1595|
|Usefulness of MRI for evaluation of neoadjuvant chemotherapy effectiveness and preoperative staging of cervical cancer|
In patients with uterine cervix cancer treated with neoadjuvant chemotherapy with uterine arteries chemoembolization the overall tumor response rate (complete response + partial response) was 70% (28/40). In 5 of 7 complete MRI responses isolated cancer cells were revealed on pathology. Residual stage IA tumor was not detected by MRI in another 1 patient. Sensitivity, specificity and accuracy of MRI in the detection of stage IA or greater residual tumor were 97%, 100% and 98% respectively.
Sensitivity, specificity and accuracy of MRI in the detection of parametrial tumor invasion and pelvic lymph nodes metastases were 73%, 77%, 76% and 44%, 90%, 85% respectively. Sensitivity of size criterion of 1 cm in a short axis for pelvic lymph nodes metastases detection is low as smaller lymph nodes may be malignant.
MRI has a high accuracy in the preoperative staging of the cervical cancer and in the diagnosis of residual tumor after neoadjuvant chemotherapy.
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ECR 2011 / C-1548
New FIGO Staging of Uterine malignancies with MR Imaging: Correlation with Surgical and Histopathologic Findings