Aims and objectives
Cardiac magnetic resonance (CMR) has an exclusive role in the noninvasive detection of myocardial inflammation.
Late gadolinium enhancement (LGE) imaging has a high sensitivity for the detection of fibrous tissue,
commonly found in myocarditis.
In acute myocarditis,
the presence of myocardial fibrosis has diagnostic and prognostic value.
LGE imaging has become a key evaluation tool in the difficult diagnosis of this disease.
Long acquisition times are a big drawback of CMR,
Methods and materials
Short axis 2D LGE and 3D LGE sequences (same spatial resolution of 1.2 x 1.2 mm²; slice- thickness 8 mm; field of view,
350 x 350 mm²) were acquired in 30 patients with epicardial and midmyocardial scars (12 female,
mean age 37.5 ± 16 years) at a 1.5T clinical scanner (Achieva,
Image quality was evaluated by two independent,
blinded readers using a 5-point Likert scale,
ranging from excellent (score: 1) to nondiagnostic (score: 5).
Myocardial and fibrotic mass...
For 21 of 30 (70%) of the 3D data sets and 22 of 30 (73.3%) of the 2D data sets,
image quality was excellent (score: 1).
Poor (score: 4) and nondiagnostic (score: 5) image quality was not found in either group.
There was no significant difference in image quality between 3D und 2D LGE acquisitions (1.5 vs 1.4,
P = 0.3) with good interreader agreement (weighted κ = 0.7 vs.
There were no significant differences between 3D and 2D LGE acquisitions for myocardial mass (111.1 g ± 32.6 vs....
In patients with myocarditis 3D LGE imaging shows equal diagnostic quality and scar visibility compared to clinically established 2D LGE sequences but with a significantly reduced acquisition time.
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Sormani P et al (2017) Quantitative changes in late gadolinium enhancement at cardiac magnetic...