Aims and objectives
Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is becoming an increasingly popular breast imaging tool especially for screening high-risk women,
staging local disease in newly diagnosed breast cancer,
and tumour evaluation during neoadjuvant treatment. While it has an excellent sensitivity,
breast MRI interpretation can be challenging.
The American College of Radiology (ACR) Breast Imaging Reporting and Data System.
(BI-RADS) lexicon is a widely accepted standard that...
Methods and materials
Patient population An anonymized database of consecutively collected histologically verified breast MRI cases (n=70,
46 benign) was read by two independent off-site fellowship trained readers.
Histopathological analysis was obtained either by image-guided biopsy (core / vacuum assisted biopsy under US/mammographic / MRI guidance) or surgical excision with the histopathological assessment done by board-certified breast pathologists. Data collection and analysis The structured...
A total of 70 lesions in 70 patients (24 malignant,
46 benign) were analysed. 51 lesions were classified as “mass” and 19 as “non-mass”. Diagnostic accuracy (area under the ROC curve,
AUC) ranged between 85.4% and 91.6%.
(Fig.2) Kaiser score reading results using the peak enhancement of either the first or second timepoint performed significantly better than the other approaches (P<0.05,
respectively). A high sensitivity level,
corresponding to a rule-out criterion,
was achieved for all...
It is well established that the time-signal intensity curve (TIC) from dynamic contrast-enhanced magnetic resonance imaging (DCE- MRI) reflects the hemodynamic features of a specific lesion. The enhancement kinetics are an important aid in characterizing breast lesions and improving delineation between benign and malignant lesions. The shape of the time-signal intensity curve is classified according to ACR BIRADS lexicon as persistent enhancing "Type 1",
plateau "Type 2",
or washout "Type...
Department of Diagnostic Imaging National University Hospital,
Singapore And Yong Loo Lin School of Medicine,
National University of Singapore
Magnetic resonance imaging of the breast: Recommendations from the EUSOMA working group,
46 (2010) 1296–1316.
doi:10.1016/j.ejca.2010.02.015.  C.