To familiar with epidemiology and pathophysiology of CNS tuberculosis. To discuss the imaging spectrum of CNS tuberculosis (TB meningitis and parenchymal TB) on CT and MRI. To know the complications of CNS tuberculosis.
caused by Mycobacterium tuberculosis ,
accounts for eight million deaths worldwide annually.
Tuberculous involvement of the central nervous system (CNS) is an important and serious type of extra-pulmonary involvement.
Approximately 10% of all patients with tuberculosis have CNS involvement.
its prevalence is greater in immunocompromised patients and is seen in upto 15% of cases of acquired immunodeficiency syndrome-related TB. CNS TB usually results from...
Findings and procedure details
Spectrum of lesions in CNS TB, Meningeal: TB meningitis Miliary and leptomeningeal granuloma Parenchymal: Tuberculous granuloma (tuberculoma) Tuberculous abscess Tuberculous encephalopathy Tuberculous cerebritis Non-osseous spinal cord tuberculosis Complications: Vasculitis and infarction Cranial neuropathy Calvarial tuberculosis,
subdural and epidural abscess. Immune Reconstruction Inflammatory Syndrome(IRIS). TB meningitis (TBM): TB meningitis is the most common manifestation of CNS.
CNS TB is a major cause of morbidity and mortality in patients with tuberculosis.
MR imaging plays a crucial role in diagnosis because of its inherent sensitivity and specificity in detecting CNS lesions earlier than CT. We conclude that conventional MRI imaging supplemented by advanced MRI techniques helps in improved detection and characterisation of CNS tuberculosis and may help in better management of these patients.
Tuberculosis of the central nervous system.
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