Resume in a practical guide for radiological use ,
the paper of different Cardiac Magnetic Resonance Imaging (CMRI) techniques to demonstrate the typical morphological characteristics and phenotypes of Hypertrophic Cardiomyopathy (HCM). Describe the interaction between different phenotypic patterns ,
functional and hemodynamic consequences,
and potential adverse events Revealthe different patterns of late gadolinium enhancement (LGE) and its correlation with fibrosis Discuss the emerging role...
Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiomyopathyandthe most common cause of Sudden cardiac death (SCD)in young athletes . HCM is caused by mutations in sarcomeric genes transmitted following an autosomal dominant pattern.There is agreat variability of phenotypes. The pathologic hallmarks of HCM are myofibrillary disarray, interstitial fibrosis and abnormal dysplasia of intramural coronary arterioles (microvascular dysfunction). Because the clinical manifestations...
Findings and procedure details
»CMRITECHNIQUES APPLIED TOHCM CMRI tecniques let us a new perspective about the frequency,
and prognosis of HCM. CINE SSFP MR IMAGING SEQUENCES (Cine Steady-state free precession) are usedto evaluate: - Cardiac function measurement Biventricular volume quantification and function Elevation of left ventricle ejection fraction(LVEF) Sistolic disfunction often develops with end-stage HCM. Assessment of global and segmental systolic thickening -Morphological aspects: Quantify the...
MRI has proven to be an important tool for the evaluation of patients suspected of having HCM Makingthe diagnosis and identifying the phenotypes of HCM Can potentially identify the subset of patients at risk of sudden cardiac death Differentiating between HCM and other myocardial diseases showing LVH (phenocopies). playing an important role in screening of the family members of a patient with HCM. Have a practical updated management guide by CMRI,
Ameya Jagdish Baxi,
MD Carlos S.
MDDaniel Vargas,Hypertrophic Cardiomyopathy fromA to Z: Genetics,
and Management.RadioGraphics 2016; 36:335–354. Barry J.
Maron and Martin S.
LGE Means Better Selection of HCM Patients for Primary Prevention Implantable Defibrillators.
JACC: Cardiovascular Imaging.Volume 9,
December 2016 Jan Bogaert,
MR Imaging in Hypertrophic Cardiomyopathy: From Magnet to Bedside.