Aims and objectives
PET-CT with F-18-FDG is often used in oncology patients diagnosis.
Respiratory movements may influence the correct evaluation of malignant lesions especially in upper abdomen and lungs.
The aim of this work is to study the influence of respiratory movements in anatomic registration and SUV determination.
Methods and materials
aged 41 to 85 years,
mean age of 64 ± 11,6 years,
with a total of 74 increased F-18-FDG uptake lesions where included. Data was acquired on a GE Discovery LS/4 PET-CT Scanner starting 60 to 90 minutes after the i.v.
administration of 18F-FDG (5 MBq/Kg of patient weight); CT acquisition used 120 kV,
80 mA and 1.5 pitch and PET acquisition on 2D mode included 5 to 6 FOV (3 minutes per bed position).
A further 1 to 2 late FOV (> 2 hours p.i.) acquisition was...
There is a statistically significant difference (p<0.001) between SUVmax values,
especially ininspiration mode.
Misregistration was found in: 6 cases - shallow breathing (50% RUL),
14 cases – expiration (29% LUL and 43% RUL) and 19 cases in inspiration (32% RUL,
21% LUL and 16% LML).
Respiratory movements have impact on image registration and SUVmax evaluation.
It is important to optimize image acquisition protocols with F-18-FDG PET-CT defining the best breathing technique,
especially for longitudinal studies.
Diogo Borges Faria,
BSc Nuclear Medicine,
PhD candidate – HPP-Medicina Molecular SA - Lenitudes Medical Center & Research; Adjunct professor at School of Health Sciences,
University of Aveiro,
Portugal; e-mail: firstname.lastname@example.org Joana Vale,
MSc; HPP-Medicina Molecular SA - Lenitudes Medical Center & Research; Radioncology – Júlio Teixeira SA (Porto) ; Professor at School of health Sciences,
University of Aveiro,
Portugal; e-mail: email@example.com Cristiana...
Techniques for respira on-induced ar facts reduc ons in thoracic PET/CT.
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Motion artifacts occurring at the lung/diaphragm interface using 4D CT attenuation correction of 4D PET scans.
Journal of Applied Clinical Medical Physics.
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4D PET/CT as a Strategy to Reduce Respiratory...