Aims and objectives
The aim of our study was the retrospective evaluation of 70 Random Prostate Biopsies (RPB).
13/70 biopsies were performed with Target Fusion Imaging (TFI).
The assessment of the different results between the two proceduress in percentage of positivity was also obtained.
TFI with a minimum number of samples in terms of positivity is able to prove the same effectiveness of RPB if the biopsy procedure is anticipated by a multiparametric-Magnetic Resonance Imaging (mp-MRI) that allows the...
Methods and materials
70 patients receiving biopsy with PSA value between 4.5 and 10 ng /ml with suspected PSA ratio,
negative for Digital Rectal Examination (DRE) and Trans-Rectal Ultrasound (TR-US).
From January 2016 to February 2017,
a working group including the Urology Unit of the S.
Eugenio Hospital ASL Roma 2 and the Diagnostic and Interventional Radiology Unit of S.
Filippo Neri Hospital ASL Roma 1,
performed 70 prostate biopsies in patients with clinical suspicion of Prostatic Cancer. 57/70 patients were...
A total of 70 biopsies were obtained .
54 were positive (77.1%) and 16 negative (22.9%).
57/70 random biopsies were carried out : 44/57 positive (77.2%) and 13/57 negative (22.8%).
13/70 targeted biopsies performed: 10/13 were positive for prostate adenocarcinoma (76.9%); 3/13 were negative (chronic inflammation) (23.1%).
In 6/13 patients pathology sampling revealed prostate adenocarcinoma with Gleason score 6 (3 + 3) and Gleason score 7 (4 + 3) in 4/13.
The percentage of positivity obtained with random biopsy (12 cores) was 77.2%.
The diagnosis of prostate carcinoma obtained with fusion biopsy (4 cores) was positive in 76.9% and target lesions scanned with mpMRI.
No major or minor complications were observed.
The deviation between the two techniques was 0.3%.
The difference between the two methods for diagnostic purposes seems to be meaningless However we should consider that the high number of cores obtained the high procedure related...
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1) Faiella E Santucci D Greco F Frauenfelder G Giacobb e Muto G Zobel BB Grasso RF Analysis of histological findings obtained combining US/mp-MRI fusion-guided biopsies with systematic US biopsies: mp-MRI role in prostate cancer detection and false negative. Radiol Med. 2017 Oct 10.
doi: 10.1007/s11547-017-0814-y. . 2) Fusco R Sansone M Granata V Setola SV Petrillo A . A systematic review on multiparametric MR imaging in prostate cancer detection. Radiology Unit,
" Istituto Nazionale Tumori -...