Aims and objectives
Intraductal Papillary Mucinous Neoplasms (IPMNs) are group of cystic neoplasm that arise in the main pancreatic duct or its branches.
They are characterized by an intraductal proliferation of mucin-producing neoplastic cells arranged in papillary formations .
The gross appearance depends on which part of the pancreatic duct system is involved and the extent of the lesion [2,
IPMNs can be morphologically distinguished in three groups: MD-IPMN (main duct IPMN),
BD-IPMN (Branch duct IPMN)...
Methods and materials
IRB approval was not required for this retrospective study,
which was conducted according to the Declaration of Helsinki,
and informed consent was waived. Patient population From a search on the PACS system of our hospital to identify patients with IPMN who underwent a MRI/MRCP with Gadolinium at our Institution,
we selected 56 consecutive patients.
The study population included 22 males and 34 females with an average age at the time of the examination of 67.4 years. MRI imaging MRI...
Among the 56 patients,
6 patients had a diagnosis of combined IPMN and 50 of branch-duct IPMN.
A total of 150 lesions were reviewed.
Each patient had a median of 2 cysts >5mm (range 1-10 cysts; mean 2.7 cysts).
The mean diameter of the cystic lesions was 12.9 mm; range 5-29 mm). The two readers showed almost perfect agreement regarding MPD dilation (k=0.937),
presence of filling defects (k=0.8855) and wall enhancement (k=0.8819).
The agreement was substantial for wall thickening (k=0.607) and...
Readers that are experienced in abdominal imaging,
when assessing IPMN at MRI/MRCP,
show an interobserver agreement ranging between substantial (0.607) and excellent (0.937).
Istituto di Radiologia Universitá di Verona Policlinico GB Rossi P.le L.A.
Scuro 10 37134 Verona Italy
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Intraductal papillary-mucinous neoplasia of the pancreas: Histopathology and molecular biology.
World J Gastrointest Surg.
2010;2(10):306-313. 3. Procacci C,