Aims and objectives
MR-guided prostate biopsy is safe but time consuming and expensive.
Accuracy of relevant PCA at multiparametric MRI and differentiation from benign and PIN lesions is still crucial and has to be increased.
PIRADS version 2 reflects the location of the tumor as well as the size by an installed Cut off of 15mm size. As a consequence of Version 2,T2wimaging of ther peripheral zone got less relevant. Study aimed to analyse,
whether or not thesize of a histologically proven prostate tumor...
Methods and materials
205 lesions of the peripheral zone and 206 of the transitional zone were histologically proven by MR-guided biopsybased on an suspiciousPIRADS Version 2 classification of a multiparametric prostate MRI.
The patients underwent an inconclusive TRUS-biopsy. All scoring points were analzyed according to PIRADS Version 1 and 2 (see examples at slides 5-15)with special focus on T2w-based scoring both at ther peripheral and transitional zone.
The largest diameter in any of the 3 dimensions was...
Histopathologic outcome of endorectyally performed MR-guided biopsy of the lesion was malignant in108/205 lesions of the peripheral zone and 101/206 of the transitional zone. Building two groups according to T2w-based scoring (1-3 predicitve for benignity; 4-5 predictive for malignany) the following results were obtained: Sensitivity,
NPV of T2w PIRADS at peripheral vs.
transitional zone were: 95.4%/95.0%; 22.7%/26.7%; 57.9%/55.5%; 81.5%/84.8%. Taking into account S1-6 the...
Size of the suspect lesions is of relevance.
With increasing size sensitivity of T2w scoring increases with a gap at 10mm.
Specificty limits usage of T2w at peripheral and transitional locations similarily and seems to be slightly more specific at the transitional zone.
If you are interested in detailed literature fell free to get in contact with me. In general PIRADS classification is well established in several languages and publications.