Aims and objectives
In the recently issued EFSUMB guidelines the use CEUS-guided biopsy is adviced in deep abdominal organs (mainly liver) to avoid necrotic areas or improve targeting of undetectable or not conspicuous lesion targets on B-mode US (1,2) These recommendations were based on a limited number of papers using small,
old case series (3) or more recent single-center experiences (4,5) that do not accurately describe the role of the CEUS-guided bioptic maneuver in the routine clinical setting The purpose...
Methods and materials
The Institutional Review Board-approved patient database was collected in each participating center during the period 2005-2016. All patients who underwent CEUS-guided biopsy of FLL with fine or cutting needles at the participating centers were included (figures 1-2) Informed consent was obtained from all of the patients All participating centers were asked to gather data regarding Rate of CEUS-guided procedures on FLL over the considered period of time Indications to the CEUS-guided...
CEUS-guided biopsies were carried out in 103 patients (68 M / 35 F,
median age 69 years,
range 31-89) with 103 FLL (median size: 20 mm; range 8-55). Twenty-six out of 103 patients (25.2%) had a previous non-diagnostic cyto-histological exam performed under non-enhanced US guidance The rate of interventionalprocedures under CEUS guidance on FLL was 2.6% of 3818 biopsies on hepatic targets (range 0.8% - 7.7%) in the 6 participating Centers Indications to CEUS-guided biopsy were 1) Detection of...
Our retrospective analysis provides a real snapshot of the use of CEUS as guiding system for liver biopsy on FLL in selected US interventional centers Although the procedure is not frequently used (less than 3% of more than 3.000 biopies on FLL),
itrepresents a safe and effective tool to cope with challenging clinical scenarios: poorly visualized or invisible lesions sampling of non-necrotic areas in the target lesions repeat biopsy after unsuccessful sampling performed using the standard...
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