Aims and objectives
CT angiography became the reference technique for exploring supra-aortic trunks.
This is an accessible,
fast and reliable technique with high spatial and contrast resolution 1 . However,
these are two disadvantages: radiation and adverse effects of contrast media (CM) 1-5 . Dual-Energy CT (DECT) is an alternative to reduce iodine load with well-established results in literature,
but few studies about quality image had been done in cervical artery 6-8 .
when reducing iodine load with...
Methods and materials
Patient population: In this single-center retrospective study,
240 consecutives patients were included at Rouen University Hospital (Normandie,
France) until September 2014 and October 2016. Data acquisition: We performed supra-aortic trunks CT angiography with the same 64 detectors width scanner (Discovery 750HD,
General Electric Healthcare,
USA) according to 3 successive protocols ( Fig. 1 : Standard Group: Single-energy CT with full-dose CM (1mL/kg of Iohexol 350 mg/mL at...
Caracteristics population ( Fig. 3 ) : There were no significant differences in sex ratio,
and examination indication between the three groups (all p>0.05).
There was no acute iodinated contrast media adverse reaction. Iodine dose : As expected,
mean iodine load was significantly lower in dual-energy groups (mean iodine load Standard = 25,48± 4,81; mean iodine load GSI 350 = 12,94± 2,62; mean iodine load GSI 270 = 13,22± 2,89g,
all p<0,01). Quality analysis: Overall quality score...
DECT with reduced iodine load is feasible and reliable for supra-aortic trunks exploration with improved image quality and reduced radiation dose,
compared to standard protocol. When reducing iodine load at DECT,
the best compromise would seem to use higher volume with lower concentration and with faster injection rate. Nevertheless this promising results need to be confirm by further studies about diagnostic accuracy of this technology.
Evaluation of carotid stenosis using CT angiography in the initial evaluation of stroke and TIA.
Neurology 2004;63(3):457‑60. Davenport MS,
Contrast Material–induced Nephrotoxicity and Intravenous Low-Osmolality Iodinated Contrast Material: Risk Stratification by Using Estimated Glomerular Filtration Rate.
Radiology 2013;268(3):719‑28. Davenport MS,