The purpose of this educational exhibit is to: Enumerate the causes of hypophysitis. To discuss the imaging spectrum and MRI features in different causes of hypophysitis.
Inflammation of the pituitary- Hypophysitis is rare and occurs much less commonly than primary tumors. The exact classification of these disorders varies among authors,
but they are generally divided into primary and secondary processes (Fig.1). Secondary hypophysitis is usually associated with an underlying systemic disorder,
whereas primary hypophysitis is isolated to the gland. Inflammation can involve anterior pituitary gland (adenohypophysitis),
posterior gland and stalk...
Findings and procedure details
1. Primary Hypophysitis: Primary hypophysitis has been histologically classified into five types: lymphocytic hypophysitis,
xanthomatous hypophysitis and necrotizing hypophysitis. Most common types being lymphocytic and granulomatous and the same have be discussed A. Lymphocytic hypophysitis Is an autoimmune disorder associated with hashimoto thyroiditis,
atrophic gastritis and pernicious anemia. It is...
MRI imaging is currently the best non-invasive diagnostic tool to differentiate hypophysitis from causes mimicking as hypophysitis.
Although the imaging findings of the primary autoimmune lymphocytic hypophysitis are usually not specific enough to distinguish this disease from adenoma,
accurate diagnosis requires a high degree of suspicion and correlation with clinical signs and symptoms.
The diagnosis of the secondary hypophysitis may be suggested when imaging abnormalities are seen in a...
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Lymphocytic hypophysitis with cystic MRI appearance.
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