The aim of this educational exhibit is: To demonstrate imaging findings of the commonly seen toxic and acquired metabolic encephalopathies which were detected on acute or chronic stage at different age groups. To emphasize the importance of the clinical background as making differential diagnosis.
Various toxins and the products of abnormally altered metabolism cause damage in brain tissue.
an important substance of brain tissue with its lipid content,
is highly vulnerable to lipophilic toxic substances.
Magnetic Resonance (MR) imaging helps to detect acutely injured brain areas associated with sudden onset of neurologic dysfunctions or squeal changes associated with permanent dysfunctions.
In case of an acute or a chronic brain damage,
involvement patterns of brain tissue on...
Findings and procedure details
1- Hepatic Encephalopathy/Acquired Hepatocerebral Degeneration Hepatic encephalopathy (HE) can occur in the setting of acute hepatic failure or as a more chronic process in patients with hepatocellular dysfunction that causes portosystemic shunt.
Acute HE can be rapidly fatal,
whereas chronic HE is usually a more indolent process as named Acquired Hepatocerebral Degeneration (AHD). The changes in mental status alterations range from subtle cognitive dysfunction to severe coma whereas the...
MR imaging has an important role on evaluating toxic and acquired metabolic encephalopathies and determining patient management.
Neurologic symptoms and brain involvement patterns have similarities and may overlap.
correct diagnosis can be made with combining typical imaging findings with sufficent clinical background data.
and quantification: final report of the working party at the 11th World Congresses of Gastroenterology,
2002 Mar 1;35(3):716-21. Krieger S,
MRI findings in chronic hepatic encephalopathy depend on portosystemic shunt: results of a controlled prospective clinical...