To illustrate intraductal papillary neoplasms of the pancreas,
and ampulla by contrasting the CT/MRI images with histological findings To provide a comprehensive understanding of these neoplasms and to summarize their characteristics.
In the WHO 2010 classification of tumors,
macroscopically recognizable papillary neoplastic lesions in the biliary system,
as counterparts of pancreatic intraductal papillary mucinous neoplasms (IPMN),
were described: lesions in the bile duct were defined as intraductal papillary neoplasm of bile duct (IPNB) and those in the gallbladder as intracholecystic papillary tubular neoplasm (ICPN).
Papillary neoplastic lesions in the papilla of Vater,
proliferating in the papillary duct (common...
Findings and procedure details
Anatomy and Embryology The pancreas and biliary tract are anatomically and embryologically related to each other. These organs are anatomically adjacent to each other and,
both arise from the foregut endoderm almost at the same time.
The ventral pancreas develops from the biliary primordium and fuses with the dorsal pancreas to form the pancreas.
the pancreas and biliary tract share the same transcription factors during their development process.
Intraductal papillary neoplasms in the pancreaticobiliary system typically develop from precancerous lesions or noninvasive cancerous lesions,
and their development is characterized by the adenoma-carcinoma sequence.
The prognosis is better than that of conventional invasive adenocarcinomas. Imaging studies showed that all cases had an elevated papillary lesion in the pancreaticobiliary area with limited invasion into the surrounding area.
Dilatation of the pancreatic or biliary duct...
Munechika Showa University School of Medicine,
Department of Radiology,
Japan Mail: firstname.lastname@example.org
Carcinoma of the gallbladder and extrahepatic bile ducts.
In: Bosman FT,
World Health Organization classification of Tumors of the Digestive System.
4 th ed.
Lyon: IARC press;2010.p266-274. Katabathina VS,
Biliary diseases with pancreatic counterparts: Cross-sectional imaging findings.
Radiographics 2016;36:374-392. Tanaka M,