Lung transplantation (LTX) recipients are exposed to repeated ionizing radiation procedures during follow-up,
potentially increasing the malignancy risk [1-4]. The purpose of this study was to evaluate the cumulative post-transplantation radiation dose in cystic fibrosis (CF) LTX recipients and to compare doses of patients with and without de novo malignancy.
Description of activity and work performed
Methods and Materials: Study design This retrospective cohort study was approved by the Institutional Review Board of the French learned society for respiratory medicine -Société de Pneumologie de Langue Française ,
which waived the need for patients’ consent (reference number CEPRO 2017-030). Patient’s characteristics All CF patients who had undergone LTX,
alone or in combination with other organ transplantation at Hôpital Européen Georges Pompidou,
between January 2001 and December 2006...
Conclusion and recommendations
CED happened to exceed the limit of 100mSv over 5 years in nearly 40% of our CF patients,
mainly because of chest CT. Even though most cancers were attributable to immunosuppression,
with no significant association found between radiation dose and de novo malignancy,
continuous attention should be paid to limit radiation exposure after lung transplantation.
Corresponding author: Pr Marie-Pierre REVEL Address: Service de Radiologie A,
groupe Hospitalier Cochin Broca Hôtel-Dieu,
27 rue du faubourg Saint-Jacques 75014 PARIS FRANCE email: firstname.lastname@example.org
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