Although breast cancer in young women is a relatively uncommon condition (approximately 7% of all breast cancer are diagnosed before the age of 40 years,
and less than 4% of female cases are diagnosed under the age of 35  ),
there has been a dramatic increase in the number of breast cancers diagnosed in premenopausal women in many parts of the world  . The diagnosis of breast cancer in young women may be challenging because of: 1) baseline dense breast tissue (which can obscure the...
Methods and Materials
We performed a retrospective review of a consecutive series of women under 35 years old with breast cancer,
who were seen in our Institute between January 2009 and July 2012.
A total of 47 women with breast cancer were identified. For all these patients clinical characteristics,
radiological features (mammography,
pathological and biological factors were retrospectively reviewed. Clinical evaluated data were age,
presence of symptoms at diagnosis (asymptomatic,
The mean age of patients at breast cancer diagnosis was 32.2 years (range 26-35 y). Presence of symptoms at diagnosis (38/47 women were symptomatic at diagnosis [Fig.1-4] ) and family history are shown in Table 1 . Table 1. Number of patients % NO FAMILY HISTORY OF BREAST CANCER 15/47 31,9 FAMILY HISTORY OF BREAST CANCER 17/47 36,2 First-degree relatives 12/47 25,6 Other relatives but no first-degree relatives 5/47 10,6 Maternal side only 11/47 23,4 Paternal side only 4/47 8,5 Both sides 3/47...
In our study,
the vast majority of patients under 35 years old still detected their tumors on self-examination,
as reported in other studies [1-2] .
The large median tumor size and the high proportion of patients with axillary node involvement reflect the shortcomings and/or the lack of current screening recommendations. To implement breast cancer surveillance in young women could be helpful in earlier detection,
even if symptoms are the most frequent presentation feature. The retrospective...
Characteristic features and usefulness of MRI in breast cancer in patients under 40 years old: correlations with conventional imaging and prognostic factors.
Breast Cancer 2012 Jun 22.
[Epub ahead of print] 2.
Rafferty E et al.
Diagnosis of breast cancer in women age 40 and younger: delays in diagnosis result from underuse of genetic testing and breast imaging. Am J Surg.
doi: 10.1016/j.amjsurg.2009.06.010. 3.
Manuela Durando firstname.lastname@example.org Istituto di Radiologia Diagnostica ed Interventistica Università di Torino Via Genova 3,
Italy Azienda Ospedaliera Città della Salute e della Scienza di Torino,
Presidio Ospedaliero Molinette