The aim of this prospective study was to evaluate the value of diffusion tensor (DT) imaging in intraspinal cord tumors . Spinal cord tumors are rare lesions,
especially when located intremedullary (1).
Despites the advances made in microsurgical neurosurgery,
operations of spinal cord tumors remains challenging. The major predictor of resectability is still the histological type of the tumor (2,
3). Conventional MR imaging has been shown to provide earlier detection of spinal cord tumors but...
Methods and Materials
Diffusion tensor imaging was performed in 24 patients with intraspinal lesions.
Lesions showed different amount of spinal cord compression or infiltration. All patients underwent MR imaging on a 3.0T magnet (Verio,
Germany) with a dedicated cervical spine coil. A standardized MR imaging protocol for the cervical spine was used including sagittal T2 (TR: 4680 TE: 105) and T1-weighted (TR: 510,
TE: 10 ) and axial T2 weighted planes as well as gadolinium enhanced T1 weighted...
: Of the 24 patients (12 male,
12 female; mean age 49.5 ± 18.1 years,
13 patients showed intramedullary tumors,
9 Patients presented extramedullary intradural tumors and2 patients had epidural masses. 6 patients had ependymomas,
5 Patients showed meningiomas,
3 patients had cavernomas,
1 patient showed a cord oligodendroglioma,
another a LGG,
1 patient had a cord Glioblastoma.
1 patient had a chordoma with mass effect on the spinal cord.
One patient presented with an...
These preliminary data suggest that DTI and Tractographies of spinal cord tumorscan be capable of showing the effect of tumors to the spinal cord with more sensitivity than conventional MRI does and thus having the potential of predicting the resectability of spinal cord tumors.
Further prospective and longitudinal studies are needed to confirm these results and effects on patient outcome. Acknowledgments: We would like to thank Siemens Healthcare (Erlangen,
Germany) for providing us with the...
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Onofrio BM: Spinal cord astrocytoma: pathological and treatment...
1.University Clinic Innsbruck,University Clinicof Neuroradiology, Anichstrasse 35,
6020 Innsbruck (F.C-Z) 2..University Clinic Innsbruck,Department of Neurosurgery,
6020 Innsbruck.(S.I,H.K,C.T) 3.University Clinic Innsbruck,
Department of Radiology, Anichstrasse 35,