To evaluate the diagnostic accuracy of MRI,
CT and CT-PET in the preoperative diagnosis and staging of gynecological malignancies to overcome the limits of the current clinical staging in order to direct Patients towards a correct surgical and therapeutical planning.
Methods and Materials
82 Patients with suspected gynecological lesion at the ultrasound were included: endometrial lesions (32),
cervical lesions (25) and ovarian lesions (25).
All Patients underwent tumor markers examination,
MRI and CT-PET to evaluate the presence of lymph node and /or distant metastasis.
Endometrial cancer: MRI sensitivity 82% and specificity 88%.
CT sensitivity 71% and specificity 72%.
CT-PET sensitivity 76% and specificity 90%.
Cervical cancer : MRI sensitivity 86% while CT and CT-PET sensitivity 75%; MRI and CT-PET specificity 88% while CT specificity 66%.
Ovarian cancer: MRI and CT-PET sensitivity 93% while CT sensitivity 86%; MRI and CT-PET specificity 90% while CT specificity 70%.Pelvic and para-aortic lymph nodes: MRI and CT sensitivity 75% while CT-PET sensitivity...
Our results direct us towards the necessity of a revision of the current guidelines for the diagnosis and staging of gynecological malignancies to obtain a more correct therapeutical planning and prognosis determination.
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