To investigate the value of second look breast US with and without contrast enhanced MR volume navigation and fusion imaging (VNav) as reference.
Methods and Materials
Twenty-four patients (52±18 years, range 33-77) with additional lesions at conventional MR underwent bilateral contrast-enhanced (0.1 mmol/Kgbw Gd- BOPTA, Bracco Diagnostics) breast MR in supine position (1.5T, Achieva, Philips Healthcare) using T1-weighted high resolution isotropic examination volume and spectral attenuated inversion recovery fat suppression with body coil. Three fiducial, pills of vitamin E on the corresponding skin markers were used. US and MR coregistration was obtained...
Thirty-one additional lesions were detected in both MR exams. Pathologic examination showed 21 malignant and 10 benign lesions. Lesions diameter was 25±12 mm (mean±SD, range 7-43). 52% (11/21) of malignant and 60% (6/10) of benign lesions were detected only using VNav (p=0.0001). MR-guided biopsy was performed in three cases. Pathology demonstrated a 9 mm DCIS, a 8 mm sclerosing adenosis and a 12 mm atypical ductal hyperplasia.
Second look US with VNav showed a significant higher detection rate for additional MR-detected lesions increasing the possibility of tissue assessment using US- guided biopsy.
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Alfonso Fausto, M.D. Consultant Radiologist, Diagnostic Imaging Department San Giovanni di Dio General Hospital Viale Fatebenefratelli, 34 34170 Gorizia - Italy Email: firstname.lastname@example.org Ludovica Borghese, M.D. Consultant Radiologist, Diagnostic Imaging Department Casa di Cura Città di Udine Viale Venezia, 410 33100 Udine, Italy Email: email@example.com Giorgio Rizzatto, M.D. Director, Diagnostic Imaging Department San Giovanni di Dio General Hospital Viale Fatebenefratelli, 34 34170...