Aims and objectives
Breast density is defined as the ratio of fibroglandular tissue to the total fibroglandular and adipose tissue in the breast .
It is important clinically because increased breast density is associated with decreased sensitivity of mammography and increased breast cancer risk .
The most widely used method of reporting breast density clinically involves visual assessment of mammographic images by radiologists,
using the American College of Radiology (ACR) four-category Breast Imaging...
Methods and materials
The dataset consisted of 375 temporal pairs of digital screening examinations,
acquired from 112 women diagnosed with histologically confirmed breast cancer.
All women had at least two screening mammography examinations (37 had two screens,
27 had three screens,
27 had four screens,
16 had five screens,
3 had six screens and 2 had seven screens) separated by an average of 12 months.
Images were obtained from a mix of manufacturers’ systems (GE,
Hologic and Siemens). Raw (“For Processing”)...
An example evolution of the mammographic density over time is shown in Fig.
5 . Image registration and standardization of mammographic images from different mammography system vendors allows breast density changes over time to be more easily visualized. The overall temporal trend of VBD according to age is demonstrated in Fig.
6. As expected,
Volpara shows that breast density gradually decreases as age increases.
The average change in VDG across a temporal series of images,
Volpara demonstrated excellent temporal consistency and reproducibility in women undergoing screening over time.
the assessment of volumetric breast density was robust to the presence of breast lesions.
Volpara Solutions Ltd firstname.lastname@example.org Ariane Chan,
Volpara Solutions Ltd email@example.com Ralph Highnam,
Volpara Solutions Ltd firstname.lastname@example.org
 Spayne MC,
Reproducibility ofBI-RADS breast density measures among community radiologists: a prospective cohortstudy.
2012; 18(4):326-33  Boyd NF,
and Yaffe MJ.
Mammographic density and the risk and detection of breast cancer.
2007; 356:227-36  Fujita H,
Muramatsu C (Eds): IWDM 2014,