Illustration oftypical and atypical imaging features of pulmonal (PTB) and extrapulmonal tuberculosis (EPTB) in HIV positive patients that could help us to make proper diagnosis and introduce adequate therapy.
The greater virulence of Mycobacterium tuberculosis , compared to other opportunistic pathogens that complicate HIV infection,
means that most patients who develop tuberculosis (TB) have not experienced other AIDS-defining infections (22) .
TB occurs at relatively high levels of CD4 + T-lymphocyte counts,
although its frequency markedly increases in patients with more severe immunosuppression.
HIV-TB cases have been observed to have severe immunosuppression at presentation,
Imaging findings OR Procedure details
A retrospective study was performed to document the radiological appearances of newly diagnosed pulmonary and extrapulmonary tuberculosis and its relationship with CD4 + T-lymphocyte count in patients with human immunodeficiency virus (HIV) co-infection.
Patients were hospitalized between 2007 and 2012 in Clinic for Infective and Tropical Diseases of Clinical Centre of Serbia inBelgrade.
Study included 17 patient,
12 males and 5 females with their age ranging from 21 years to 52 years,
Study’s significance is reflected in realizing the variability of appearance of tuberculosis in HIV seropositive patients,
here presented in its radiology findings.
It is because the diagnosis of TB in HIV/AIDS patients is difficult and current diagnostic tools perform badly in HIV-positive patients.
WHO guidelines recommend screening for TB in all HIV/AIDS patients,
so there is an urgent need to develop rapid,
specific and sensitive tuberculosis diagnostic tools for...
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Dr Natasa Pujic Stanisavljev,
Department of Radiology,
General Hospital Sremska Mitrovica,Serbia,