The purposes of our educational exhibit are:
To describe the basic principles of diffusion tensor imaging (DTI) and tractography.
To present normal DTI and fiber tractographic anatomy in healthy brains.
To illustrate with different cases the role of DTI and tractography in pathologic brains,
specifically in tumoral conditions.
To understand the clinical transcendence of this technique for preoperative mapping.
DTI with fiber tractography is the only non-invasive technique that enables in vivo dissection of the white substance.
This technique can study the projection,
association and commissural fibers and enables to visualize the integrity of white matter tracts surrounding some lesions.
This information results useful for the planification of biopsies or resection and can be an important complement to conventional MR imaging.
The basics of DTI and tractography
Diffusion is a...
Findings and procedure details
We retrospectively collected several cases with DTI and tractography,
both in physiological and pathological conditions,
specifically in patients with different brain tumors,
to review the normal anatomy of the white matter tracts and to analyse the influence of brain tumors in the position and the integrity of these tracts,
as well as to highlight the importance of DTI with tractography in preoperative mapping.
Normal anatomy of white matter fiber tracts
DTI with fiber tractography is one of the most remarkable advances in the field of neuroimaging in the past decade.
This method offers in vivo visualization of water diffusion along neuronal fiber tracts,
which can be used to study the normal anatomy of white matter fascicles.
As a clinical tool,
it can be used in different pathological conditions,
emphasizing its role in surgical planning to identify a safety margin around eloquent tracts in brain tumoral pathology.
Diffusion Tensor Imaging of Cerebral White Matter: A Pictorial Review of Physics,
Fiber Tract Anatomy,
and Tumor Imaging Patterns.
Am J Neuroradiol 2004;25:356-369.
Diffusion Tensor MR Imaging and Fiber Tractography: Theoretic Underpinnings.
Am J Neuroradiol 2008;29:632-641.