To briefly review the most common collagen vascular diseases (CVDs) which may have pulmonary involvement. To recognize typical and atypical chest High-Resolution Computed Tomography (HRCT) pulmonary and extrapulmonary imaging findings.
CVDs constitute a group of autoimmune disorders,
whose common denominator is the damage to components of connective tissue,
frequently targeting pulmonary interstitium,
and pulmonary vasculature. (1,2) Diagnosis of these conditions is often challenging,
while management concentrates on controlling inflammation and preventing damage,
since most of them respond well to immunosuppressant therapy. (3,4,5) The two thoracic manifestations with the greatest clinical impact in...
Findings and procedure details
Indications to HRCT HRCT is considered the imaging technique of choice for the detection and characterization of ILD in patients with CVD.
Indications to HRCT in patients with CVD include: baseline evaluations at CVD diagnosis when pulmonary involvement is suspected; monitoring of therapy when pulmonary involvement is proved; targeting of biopsy. (7,13,14) 2.
HRCT Technique The use of thin-section CT images (slice thickness ranging from 0.625 mm to 1.5 mm) with a high spatial frequency...
Chest HRCT allows assessment of interstitial lung involvement and of extrapulmonary manifestations in patients with CVDs; most cases show a non-specific interstitial pneumonia (NSIP) pattern. Chest HRCT features of CVDs may suggest clinical entities and influence management before final diagnosis.
Interstitial lung diseases associated with collagen vascular diseases: radiologic and histopathologic findings.
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