To illustrate imaging findings (mammogram,
MR) in spindle cell lesions of the breast with pathologic correlation.
To review diagnostic features and tips for correlation in imaging and pathology.
The term spindle cell lesion refers to a broad group of entities ranging from reactive processes to aggressive malignant tumours,
which are composed of cells with the typical morphological apperance of spindle cells.
Their origin is most frequently mammary epithelial cells with metaplastic changes to spindle mesenchymal-like cells.
But also myoepithelial cells may proliferate showing different morphological appearances,
Findings and procedure details
Practical approach classification Fig. 2 .
1.Bland-looking breast spindle cell lesions.
Reactive and neoplastic mesenchymal and epithelial/myoepithelial lesions that can be classified as:
1.1. Lesions of mesenchymal fibroblastic/myofibroblastic origin.
Scar Fig. 3 .
It is the most frequently found spindle cell lesion.
usually with a history of surgery or trauma.
Different spindle cell lesions may be found either benign or malignant and radiologists should be familiar with imaging findings in order to recognize them.
Always consider the possibility of metaplastic carcinoma,
the most important differential diagnosis.
Lorente Ramos1 (firstname.lastname@example.org)
Azpeitia Arman 1
Unidad Central de Radiodiagnóstico de la CAM: Hospital Infanta Leonor 1
Hospital Infanta Leonor 2
Rakha EA, Aleskandarany MA,
An approach to the diagnosis of spindle cell lesions of the breast.
Mesenchymal tumours of the breast and their mimics: a review with approach to diagnosis.
Phyllodes tumours of the breast: a consensus review.