To analyze imaging findings of cholangiocarcinoma based on morphologic classification.
To describe its radiological features and pathological correlation.
To discuss the role of interventional radiology as palliation treatment in malignant biliary obstruction and rupture.
Cholangiocarcinoma is a primary tumor arising from the bile duct epithelium and is the second most common primary hepatobiliary cancer after hepatocellular carcinoma.
At histopathologic analysis,
cholangiocarcinomas are predominantly adenocarcinomas (95% of cases),
although other histologic types have also been described.
Cholangiocarcinoma is mainly a tumor of the elderly,
with peak prevalence during the 7th decade of life and a slight male predilection.
Imaging plays a role in...
Findings and procedure details
Cholangiocarcinoma can be classified as mass-forming,
and intraductal type.
Biliary dilatation is the most common indirect sign with the “abrupt change” in ductal diameter.
US remains a screening modality in patients with jaundice.
cholangiocarcinoma is hypo-attenuating relative to the normal hepatic parenchyma; most show contrast-enhancement only during tardive delayed phase,
finding that reflect its hypovascular desmoplastic composition.
The imaging manifestations of cholangiocarcinomas are extremely diverse,
since these tumors vary greatly in growth pattern and location.
The accurate detection,
and assessment of the resectability of the tumor are the primary goals of imaging.
Recent advances in imaging techniques aid in the accurate diagnosis and evaluation of cholangiocarcinomas in preparation for advanced surgical procedures and treatment planning.
An accurate radiological classification of...
address: Università Campus Bio-medico di Roma
Via Alvaro del Portillo,
Chung YE et al.
Varying appearances of Cholangiocarcinoma: radiologic-pathologic correlation.
Sainani NI et al.
Cholangiocarcinoma: current and novel imaging tecniques.
Fu Y et al.
Radiofrequency ablation in the managment of unresectable intrahepatic cholangiocarcinoma.
J Vasc Interv Radiol 2012